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In this panel, depicting the Virgin and Child enthroned, with scenes of the Nativity and the Lives of the Saints, the Virgin is wearing a Byzantine crown and is seated on a lion-headed throne; she holds Christ on her lap. In the corners of the central section are the symbols of the four Evangelists.
The eight smaller scenes on either side of the Virgin show episodes from the lives of saints: John the Evangelist, Benedict, Nicholas, Catherine and Margaret, as well as a Nativity with the Annunciation to the Shepherds.
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