Members of the family were important in the change from Gothic to Renaissance architecture in 16th-century Spain, working mainly in Castile. Juan Gil de Hontañón the Elder (c. 1480-1526) linked the Hispano-Flemish (Isabelline) style of Late Gothic to the beginnings of Plateresque, which was further developed by his son Juan Gil de Hontañón the Younger (active 1521-1531). Another, illegitimate, son Rodrigo Gil de Hontañón (1500-1577) is regarded as particularly representative of Spanish Renaissance architecture.