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This painting depicts the Madonna giving her girdle to St Thomas, with Sts Margaret, Gregory, Augustine, Raphael, and Tobias. There is a donor portrait of a kneeling nun, probably the abbess of Santa Margherita, a small Augustinian nunnery in Prato, where Fra Filippo was awarded the chaplaincy in 1456.
Technical and stylistic evidence suggests that the picture was executed in two campaigns - designed and begun by Lippi and finished later by Fra Diamante.
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